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Target
Leukotriene B4 receptor 1
Ligand
BDBM50037391
Substrate
n/a
Meas. Tech.
ChEMBL_99829 (CHEMBL709859)
Ki
1±n/a nM
Citation
 Daines, RA; Chambers, PA; Eggleston, DS; Foley, JJ; Griswold, DE; Haltiwanger, RC; Jakas, DR; Kingsbury, WD; Martin, LD; Pendrak, I (E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid and related compounds: high affinity leukotriene B4 receptor antagonists. J Med Chem 37:3327-36 (1994) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50037391
Synonyms:
5-{2-(2-Carboxy-ethyl)-3-[6-(4-oxo-8-propyl-chroman-7-yloxy)-hexyl]-phenoxy}-pentanoic acid | CHEMBL95453 | Ro-25-3562
Type:
Small organic molecule
Emp. Form.:
C32H42O8
Mol. Mass.:
554.6711
SMILES:
CCCc1c(OCCCCCCc2cccc(OCCCCC(O)=O)c2CCC(O)=O)ccc2C(=O)CCOc12
Structure:
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