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Target
D(2) dopamine receptor
Ligand
BDBM50492799
Substrate
n/a
Meas. Tech.
ChEMBL_975879 (CHEMBL2415528)
Ki
1900±n/a nM
Citation
 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579. Eur J Med Chem 66:122-34 (2013) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50492799
Synonyms:
CHEMBL2414354
Type:
Small organic molecule
Emp. Form.:
C22H25ClN4O
Mol. Mass.:
396.913
SMILES:
Clc1ccc(cc1)-n1cc(COCCN2CCN(CC2)c2ccccc2)cn1
Structure:
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