Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50029490
Substrate
n/a
Meas. Tech.
ChEMBL_99656 (CHEMBL704422)
IC50
6.4±n/a nM
Citation
 Harper, RW; Jackson, WT; Froelich, LL; Boyd, RJ; Aldridge, TE; Herron, DK Leukotriene B4 (LTB4) receptor antagonists: a series of (hydroxyphenyl)pyrazoles. J Med Chem 37:2411-20 (1994) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50029490
Synonyms:
4-Ethyl-5-[6-methyl-6-(1H-tetrazol-5-yl)-heptyloxy]-2-(1H-pyrazol-3-yl)-phenol | CHEMBL407983
Type:
Small organic molecule
Emp. Form.:
C20H28N6O2
Mol. Mass.:
384.4753
SMILES:
CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1
Structure:
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