Reaction Details Report a problem with these data
Target
Retinoic acid receptor RXR-gamma
Ligand
BDBM50040013
Substrate
n/a
Meas. Tech.
ChEMBL_196648 (CHEMBL800761)
Kd
135±n/a nM
Citation
 Boehm, MF; Zhang, L; Badea, BA; White, SK; Mais, DE; Berger, E; Suto, CM; Goldman, ME; Heyman, RA Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids. J Med Chem 37:2930-41 (1994) [PubMed]  Article 
Target
Name:
Retinoic acid receptor RXR-gamma
Synonyms:
Nr2b3 | RXRG_MOUSE | Retinoid X receptor gamma | Rxrg
Type:
PROTEIN
Mol. Mass.:
50900.28
Organism:
Mus musculus
Description:
ChEMBL_196589
Residue:
463
Sequence:
MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERILEAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDSFLMEMLETPLQIT
  
Inhibitor
Name:
BDBM50040013
Synonyms:
4-(3-Chloro-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-benzoic acid | CHEMBL102039
Type:
Small organic molecule
Emp. Form.:
C22H23ClO3
Mol. Mass.:
370.869
SMILES:
CC1(C)CCC(C)(C)c2cc(C(=O)c3ccc(cc3)C(O)=O)c(Cl)cc12
Structure:
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