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Target
Adenosine receptor A1
Ligand
BDBM50042194
Substrate
n/a
Meas. Tech.
ChEBML_29009
Ki
76±n/a nM
Citation
 Müller, CE; Shi, D; Manning, M; Daly, JW Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors. J Med Chem 36:3341-9 (1993) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50042194
Synonyms:
8-Cyclohexyl-1-ethyl-3,7-dihydro-purine-2,6-dione | CHEMBL112587
Type:
Small organic molecule
Emp. Form.:
C13H18N4O2
Mol. Mass.:
262.3076
SMILES:
CCn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCCC1
Structure:
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