Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM26991
Substrate
n/a
Meas. Tech.
ChEMBL_1288553 (CHEMBL3118986)
Ki
89000000±n/a nM
Citation
 Nishimori, I; Vullo, D; Minakuchi, T; Scozzafava, A; Osman, SM; AlOthman, Z; Capasso, C; Supuran, CT Anion inhibition studies of two new ?-carbonic anhydrases from the bacterial pathogen Legionella pneumophila. Bioorg Med Chem Lett 24:1127-32 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM26991
Synonyms:
CHEMBL1689285 | HSO3- | bisulfite | hydrogen sulfite
Type:
Ion
Emp. Form.:
HO3S
Mol. Mass.:
81.072
SMILES:
OS([O-])=O
Structure:
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