Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 2
Ligand
BDBM50043760
Substrate
n/a
Meas. Tech.
ChEMBL_72449 (CHEMBL682619)
Ki
48300±n/a nM
Citation
 Lyttle, MH; Hocker, MD; Hui, HC; Caldwell, CG; Aaron, DT; Engqvist-Goldstein, A; Flatgaard, JE; Bauer, KE Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis. J Med Chem 37:189-94 (1994) [PubMed]  Article 
Target
Name:
Glutathione S-transferase Mu 2
Synonyms:
GST class-mu 2 | GST4 | GSTM2 | GSTM2-2 | GSTM2_HUMAN | Glutathione S-transferase Mu 2
Type:
PROTEIN
Mol. Mass.:
25743.85
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1441153
Residue:
218
Sequence:
MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
  
Inhibitor
Name:
BDBM50043760
Synonyms:
2-Amino-4-[1-[(carboxy-phenyl-methyl)-carbamoyl]-2-(4-chloro-benzylsulfanyl)-ethylcarbamoyl]-butyric acid | CHEMBL442360
Type:
Small organic molecule
Emp. Form.:
C23H26ClN3O6S
Mol. Mass.:
507.987
SMILES:
NC(CCC(=O)NC(CSCc1ccc(Cl)cc1)C(=O)NC(C(O)=O)c1ccccc1)C(O)=O
Structure:
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