Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM50043763
Substrate
n/a
Meas. Tech.
ChEMBL_72448 (CHEMBL682618)
Ki
2100±n/a nM
Citation
 Lyttle, MH; Hocker, MD; Hui, HC; Caldwell, CG; Aaron, DT; Engqvist-Goldstein, A; Flatgaard, JE; Bauer, KE Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis. J Med Chem 37:189-94 (1994) [PubMed]  Article 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM50043763
Synonyms:
2-Amino-4-[1-(2-carboxy-ethylcarbamoyl)-2-(4-methyl-benzylsulfanyl)-ethylcarbamoyl]-butyric acid | CHEMBL301229
Type:
Small organic molecule
Emp. Form.:
C19H27N3O6S
Mol. Mass.:
425.499
SMILES:
Cc1ccc(CSCC(NC(=O)CCC(N)C(O)=O)C(=O)NCCC(O)=O)cc1
Structure:
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