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Target
Mas-related G-protein coupled receptor member X1
Ligand
BDBM50336912
Substrate
n/a
Meas. Tech.
ChEMBL_1436305 (CHEMBL3388386)
EC50
316±n/a nM
Citation
 Hin, N; Alt, J; Zimmermann, SC; Delahanty, G; Ferraris, DV; Rojas, C; Li, F; Liu, Q; Dong, X; Slusher, BS; Tsukamoto, T Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors. Bioorg Med Chem 22:5831-7 (2014) [PubMed]  Article 
Target
Name:
Mas-related G-protein coupled receptor member X1
Synonyms:
MRGX1_MOUSE | Mas-related G-protein coupled receptor member C11 | Mas-related G-protein coupled receptor member X1 | Mrgc11 | Mrgprc11 | Mrgprx1 | Sensory neuron-specific G-protein coupled receptor 1
Type:
PROTEIN
Mol. Mass.:
36822.23
Organism:
Mus musculus
Description:
ChEMBL_109490
Residue:
322
Sequence:
MDPTISSHDTESTPLNETGHPNCTPILTLSFLVLITTLVGLAGNTIVLWLLGFRMRRKAISVYILNLALADSFFLCCHFIDSLLRIIDFYGLYAHKLSKDILGNAAIIPYISGLSILSAISTERCLCVLWPIWYHCHRPRNMSAIICALIWVLSFLMGILDWFSGFLGETHHHLWKNVDFIITAFLIFLFMLLSGSSLALLLRILCGPRRKPLSRLYVTIALTVMVYLICGLPLGLYLFLLYWFGVHLHYPFCHIYQVTAVLSCVNSSANPIIYFLVGSFRQHRKHRSLKRVLKRALEDTPEEDEYTDSHLHKTTEISESRY
  
Inhibitor
Name:
BDBM50336912
Synonyms:
Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide | CHEMBL1672380
Type:
Small organic molecule
Emp. Form.:
C26H38N6O3
Mol. Mass.:
482.6183
SMILES:
[#7]\[#6](-[#7])=[#7]/[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)C12[#6]-[#6]-3-[#6]-[#6](-[#6]-[#6](-[#6]-3)-[#6]1)-[#6]2)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r,TLB:9:11:14:18.17.16,9:11:18:14.15.16,20:11:18:14.15.16,THB:20:15:18:12.11.19,19:11:14:18.17.16,19:17:14:12.11.20|
Structure:
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