Reaction Details Report a problem with these data
Target
Mas-related G-protein coupled receptor member X1
Ligand
BDBM50412987
Substrate
n/a
Meas. Tech.
ChEMBL_1436303 (CHEMBL3388384)
EC50
25±n/a nM
Citation
 Hin, N; Alt, J; Zimmermann, SC; Delahanty, G; Ferraris, DV; Rojas, C; Li, F; Liu, Q; Dong, X; Slusher, BS; Tsukamoto, T Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors. Bioorg Med Chem 22:5831-7 (2014) [PubMed]  Article 
Target
Name:
Mas-related G-protein coupled receptor member X1
Synonyms:
MRGPRX1 | MRGX1 | MRGX1_HUMAN | SNSR3 | SNSR4
Type:
PROTEIN
Mol. Mass.:
36253.68
Organism:
Homo sapiens (Human)
Description:
ChEMBL_516621
Residue:
322
Sequence:
MDPTISTLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNAFSIYILNLAAADFLFLSGRLIYSLLSFISIPHTISKILYPVMMFSYFAGLSFLSAVSTERCLSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLCGFLFSGADSAWCQTSDFITVAWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFLFLWIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDASEVDEGGGQLPEEILELSGSRLEQ
  
Inhibitor
Name:
BDBM50412987
Synonyms:
CHEMBL475965
Type:
Small organic molecule
Emp. Form.:
C29H30N6O3
Mol. Mass.:
510.5869
SMILES:
COc1ccc(cn1)-c1ccc(cc1)C(=O)Nc1cccc(Cn2ncc(cc2=O)N2CCNCC2)c1C
Structure:
Search PDB for entries with ligand similarity: