Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50002765
Substrate
n/a
Meas. Tech.
ChEMBL_207650 (CHEMBL811632)
Ki
650±n/a nM
Citation
 Nicolaï, E; Goyard, J; Benchetrit, T; Teulon, JM; Caussade, F; Virone, A; Delchambre, C; Cloarec, A Synthesis and structure-activity relationships of novel benzimidazole and imidazo[4,5-b]pyridine acid derivatives as thromboxane A2 receptor antagonists. J Med Chem 36:1175-87 (1993) [PubMed]  Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50002765
Synonyms:
BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid (BM 13177) | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid(sulotroban)
Type:
Small organic molecule
Emp. Form.:
C16H17NO5S
Mol. Mass.:
335.375
SMILES:
OC(=O)COc1ccc(CCNS(=O)(=O)c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: