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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM28699
Substrate
n/a
Meas. Tech.
ChEMBL_154537 (CHEMBL760257)
EC50
600000±n/a nM
Citation
 Willson, TM; Cobb, JE; Cowan, DJ; Wiethe, RW; Correa, ID; Prakash, SR; Beck, KD; Moore, LB; Kliewer, SA; Lehmann, JM The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 39:665-8 (1996) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
Nr1c3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG_MOUSE | Pparg
Type:
PROTEIN
Mol. Mass.:
57593.55
Organism:
Mus musculus
Description:
ChEMBL_1453700
Residue:
505
Sequence:
MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQLLHVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM28699
Synonyms:
2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMBL683 | Clofibrate | Clofibrinic acid | clofibric acid
Type:
Small organic molecule
Emp. Form.:
C10H11ClO3
Mol. Mass.:
214.646
SMILES:
CC(C)(Oc1ccc(Cl)cc1)C(O)=O
Structure:
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