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Target
Transmembrane domain-containing protein TMIGD3
Ligand
BDBM89114
Substrate
n/a
Meas. Tech.
ChEMBL_1543581 (CHEMBL3750699)
Ki
380±n/a nM
Citation
 Ranganathan, A; Stoddart, LA; Hill, SJ; Carlsson, J Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models. J Med Chem 58:9578-90 (2015) [PubMed]  Article 
Target
Name:
Transmembrane domain-containing protein TMIGD3
Synonyms:
TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3
Type:
PROTEIN
Mol. Mass.:
30335.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_114868
Residue:
266
Sequence:
MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM
  
Inhibitor
Name:
BDBM89114
Synonyms:
MLS-0463381.0001 | N-(5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-2-yl)-1-benzothiophene-2-carboxamide | N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)-1-benzothiophene-2-carboxamide | N-(5,6-dihydro-4H-cyclopenta[d]thiazol-2-yl)benzothiophene-2-carboxamide | cid_25553043
Type:
Small organic molecule
Emp. Form.:
C15H12N2OS2
Mol. Mass.:
300.399
SMILES:
O=C(Nc1nc2CCCc2s1)c1cc2ccccc2s1
Structure:
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