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Target
Beta-galactoside alpha-2,6-sialyltransferase 1
Ligand
BDBM50501643
Substrate
n/a
Meas. Tech.
ChEMBL_1656606 (CHEMBL4006076)
Ki
16±n/a nM
Citation
 Guo, J; Li, W; Xue, W; Ye, XS Transition State-Based Sialyltransferase Inhibitors: Mimicking Oxocarbenium Ion by Simple Amide. J Med Chem 60:2135-2141 (2017) [PubMed]  Article 
Target
Name:
Beta-galactoside alpha-2,6-sialyltransferase 1
Synonyms:
Alpha 2,6-ST 1 | B-cell antigen CD75 | Beta-galactoside alpha-2,6-sialyltransferase 1 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1 | ST6Gal I | ST6GalI | Sialyltransferase 1 | SIAT1_HUMAN | ST6GAL1 | SIAT1
Type:
PROTEIN
Mol. Mass.:
46622.19
Organism:
Human
Description:
ChEMBL_109837
Residue:
406
Sequence:
MIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRGRQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC
  
Inhibitor
Name:
BDBM50501643
Synonyms:
CHEMBL4065191
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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