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Target
Mu-type opioid receptor
Ligand
BDBM50502785
Substrate
n/a
Meas. Tech.
ChEMBL_1808888 (CHEMBL4308247)
IC50
89±n/a nM
Citation
 Rosas, R; Huang, XP; Roth, BL; Dockendorff, C ?-Fluorofentanyls Are pH-Sensitive Mu Opioid Receptor Agonists. ACS Med Chem Lett 10:1353-1356 (2019) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50502785
Synonyms:
CHEMBL4550454
Type:
Small organic molecule
Emp. Form.:
C22H25F3N2O
Mol. Mass.:
390.4419
SMILES:
CCC(=O)N(C1CCN(CC(F)c2ccc(F)cc2F)CC1)c1ccccc1
Structure:
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