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Target
Retinoic acid receptor alpha
Ligand
BDBM50053093
Substrate
n/a
Meas. Tech.
ChEMBL_195184 (CHEMBL801817)
IC50
600±n/a nM
Citation
 Muccio, DD; Brouillette, WJ; Alam, M; Vaezi, MF; Sani, BP; Venepally, P; Reddy, L; Li, E; Norris, AW; Simpson-Herren, L; Hill, DL Conformationally defined 6-s-trans-retinoic acid analogs. 3. Structure-activity relationships for nuclear receptor binding, transcriptional activity, and cancer chemopreventive activity. J Med Chem 39:3625-35 (1996) [PubMed]  Article 
Target
Name:
Retinoic acid receptor alpha
Synonyms:
Nr1b1 | RARA_MOUSE | Rara
Type:
PROTEIN
Mol. Mass.:
50742.79
Organism:
Mus musculus
Description:
ChEMBL_195182
Residue:
462
Sequence:
MASNSSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTSLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFDVGMSKESVRNDRNKKKKEAPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDKVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGLDTLSGQSGGGTRDGGGLAPPPGSCSPSLSPSSHRSSPATQSP
  
Inhibitor
Name:
BDBM50053093
Synonyms:
(2E,4E,6E)-8-Cyclohex-2-en-(E)-ylidene-3,7-dimethyl-octa-2,4,6-trienoic acid | CHEMBL121659
Type:
Small organic molecule
Emp. Form.:
C16H20O2
Mol. Mass.:
244.3288
SMILES:
C\C(\C=C\C=C(/C)\C=C1/CCCC=C1)=C/C(O)=O |c:12|
Structure:
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