Reaction Details Report a problem with these data
Target
Histone deacetylase 11
Ligand
BDBM50283689
Substrate
n/a
Meas. Tech.
ChEMBL_1829490 (CHEMBL4329364)
IC50
290±n/a nM
Citation
 Fleming, CL; Natoli, A; Schreuders, J; Devlin, M; Yoganantharajah, P; Gibert, Y; Leslie, KG; New, EJ; Ashton, TD; Pfeffer, FM Highly fluorescent and HDAC6 selective scriptaid analogues. Eur J Med Chem 162:321-333 (2019) [PubMed]  Article 
Target
Name:
Histone deacetylase 11
Synonyms:
HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11
Type:
Chromatin regulator; hydrolase; repressor
Mol. Mass.:
39187.66
Organism:
Homo sapiens (Human)
Description:
Q96DB2
Residue:
347
Sequence:
MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
  
Inhibitor
Name:
BDBM50283689
Synonyms:
CHEMBL4160632
Type:
Small organic molecule
Emp. Form.:
C22H25N3O5
Mol. Mass.:
411.451
SMILES:
ONC(=O)CCCCCN1C(=O)c2cccc3c(ccc(C1=O)c23)N1CCOCC1
Structure:
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