Reaction Details Report a problem with these data
Target
Protein lin-28 homolog A
Ligand
BDBM50507403
Substrate
n/a
Meas. Tech.
ChEMBL_1829893 (CHEMBL4329767)
IC50
11000±n/a nM
Citation
 Lim, D; Byun, WG; Park, SB Restoring Let-7 microRNA Biogenesis Using a Small-Molecule Inhibitor of the Protein-RNA Interaction. ACS Med Chem Lett 9:1181-1185 (2018) [PubMed]  Article 
Target
Name:
Protein lin-28 homolog A
Synonyms:
CSDD1 | LIN28 | LIN28A | LN28A_HUMAN | Lin-28A | Protein lin-28 homolog A | ZCCHC1 | Zinc finger CCHC domain-containing protein 1
Type:
PROTEIN
Mol. Mass.:
22749.72
Organism:
Homo sapiens
Description:
ChEMBL_119331
Residue:
209
Sequence:
MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQGKPTYFREEEEEIHSPTLLPEAQN
  
Inhibitor
Name:
BDBM50507403
Synonyms:
CHEMBL4438300
Type:
Small organic molecule
Emp. Form.:
C16H9Cl4N3O2
Mol. Mass.:
417.074
SMILES:
NC(=O)c1c(Nc2ccc(Cl)cc2Cl)[nH]c2c(Cl)c(Cl)ccc2c1=O
Structure:
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