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Target
Regulatory protein E2
Ligand
BDBM50060973
Substrate
n/a
Meas. Tech.
ChEMBL_81576 (CHEMBL689336)
Kd
>10000000±n/a nM
Citation
 Hajduk, PJ; Dinges, J; Miknis, GF; Merlock, M; Middleton, T; Kempf, DJ; Egan, DA; Walter, KA; Robins, TS; Shuker, SB; Holzman, TF; Fesik, SW NMR-based discovery of lead inhibitors that block DNA binding of the human papillomavirus E2 protein. J Med Chem 40:3144-50 (1997) [PubMed]  Article 
Target
Name:
Regulatory protein E2
Synonyms:
E2 | Human papillomavirus regulatory protein E2 | VE2_HPV16
Type:
PROTEIN
Mol. Mass.:
41834.37
Organism:
Human papillomavirus type 16
Description:
ChEMBL_532980
Residue:
365
Sequence:
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPEIIRQHLANHPAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCTLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
  
Inhibitor
Name:
BDBM50060973
Synonyms:
4'-Nitro-biphenyl-4-carboxylic acid | CHEMBL109066
Type:
Small organic molecule
Emp. Form.:
C13H9NO4
Mol. Mass.:
243.2149
SMILES:
OC(=O)c1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O
Structure:
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