Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50510879
Substrate
n/a
Meas. Tech.
ChEMBL_1842421 (CHEMBL4342848)
Ki
524±n/a nM
Citation
 Ali, EMH; Abdel-Maksoud, MS; Oh, CH Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. Bioorg Med Chem 27:1159-1194 (2019) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50510879
Synonyms:
CHEMBL4548341
Type:
Small organic molecule
Emp. Form.:
C10H11N3O2S
Mol. Mass.:
237.278
SMILES:
CC(=O)Nc1nc2sc(C)c(C)c2c(=O)[nH]1
Structure:
Search PDB for entries with ligand similarity: