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Target
Genome polyprotein
Ligand
BDBM50065871
Substrate
n/a
Meas. Tech.
ChEMBL_158967 (CHEMBL766325)
IC50
60000±n/a nM
Citation
 Yoakim, C; Ogilvie, WW; Cameron, DR; Chabot, C; Guse, I; Haché, B; Naud, J; O'Meara, JA; Plante, R; Déziel, R beta-Lactam derivatives as inhibitors of human cytomegalovirus protease. J Med Chem 41:2882-91 (1998) [PubMed]  Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM50065871
Synonyms:
(2S,3S)-2-Benzyl-3-ethyl-4-oxo-azetidine-1-carboxylic acid (pyridin-4-ylmethyl)-amide | CHEMBL319173
Type:
Small organic molecule
Emp. Form.:
C19H21N3O2
Mol. Mass.:
323.3889
SMILES:
CC[C@H]1[C@H](Cc2ccccc2)N(C(=O)NCc2ccncc2)C1=O
Structure:
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