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Target
Serine/threonine-protein kinase 16
Ligand
BDBM50511375
Substrate
n/a
Meas. Tech.
ChEMBL_1844759 (CHEMBL4345186)
Ki
510±n/a nM
Citation
 Wells, C; Couņago, RM; Limas, JC; Almeida, TL; Cook, JG; Drewry, DH; Elkins, JM; Gileadi, O; Kapadia, NR; Lorente-Macias, A; Pickett, JE; Riemen, A; Ruela-de-Sousa, RR; Willson, TM; Zhang, C; Zuercher, WJ; Zutshi, R; Axtman, AD SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K. ACS Med Chem Lett 11:340-345 (2020) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase 16
Synonyms:
MPSK1 | PKL12 | STK16 | STK16_HUMAN | Serine/threonine-protein kinase 16 | TSF1 | Tyrosine-protein kinase STK16 (STK16)
Type:
Protein
Mol. Mass.:
34659.07
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
305
Sequence:
MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQHTTQI
  
Inhibitor
Name:
BDBM50511375
Synonyms:
CHEMBL4593649
Type:
Small organic molecule
Emp. Form.:
C24H21FN4O3S
Mol. Mass.:
464.512
SMILES:
Fc1cccc(CS(=O)(=O)Nc2cccc(c2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)c1
Structure:
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