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Target
L-lactate dehydrogenase A chain
Ligand
BDBM50031638
Substrate
n/a
Meas. Tech.
ChEMBL_96428 (CHEMBL706376)
Ki
2000±n/a nM
Citation
 Deck, LM; Royer, RE; Chamblee, BB; Hernandez, VM; Malone, RR; Torres, JE; Hunsaker, LA; Piper, RC; Makler, MT; Vander Jagt, DL Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum. J Med Chem 41:3879-87 (1998) [PubMed]  Article 
Target
Name:
L-lactate dehydrogenase A chain
Synonyms:
LDH muscle subunit | LDH-A | Cell proliferation-inducing gene 19 protein | L-lactate dehydrogenase A Chain | Renal carcinoma antigen NY-REN-59 | LDH-M | L-lactate dehydrogenase A | Lactate dehydrogenase A (LDHA) | LDHA_HUMAN | LDHA
Type:
Protein
Mol. Mass.:
36694.85
Organism:
Human
Description:
P00338::PDB Code: 4ajp
Residue:
332
Sequence:
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
  
Inhibitor
Name:
BDBM50031638
Synonyms:
2,3-Dihydroxy-4-isopropyl-6-methyl-naphthalene-1-carboxylic acid | CHEMBL310405
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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