Reaction Details Report a problem with these data
Target
Potassium voltage-gated channel subfamily A member 3
Ligand
BDBM50067881
Substrate
n/a
Meas. Tech.
ChEMBL_91591 (CHEMBL703395)
Kd
28000±n/a nM
Citation
 Wulff, H; Rauer, H; Düring, T; Hanselmann, C; Ruff, K; Wrisch, A; Grissmer, S; Hänsel, W Alkoxypsoralens, novel nonpeptide blockers of Shaker-type K+ channels: synthesis and photoreactivity. J Med Chem 41:4542-9 (1998) [PubMed]  Article 
Target
Name:
Potassium voltage-gated channel subfamily A member 3
Synonyms:
KCNA3_MOUSE | Kcna3 | MK3 | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel subunit Kv1.3
Type:
PROTEIN
Mol. Mass.:
58553.58
Organism:
Mus musculus
Description:
ChEMBL_1513943
Residue:
528
Sequence:
MTVVPGDHLLEPEAAGGGGGDPPQGGCGSGGGGGGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
  
Inhibitor
Name:
BDBM50067881
Synonyms:
4,9-Diethoxy-furo[3,2-g]chromen-7-one | CHEMBL342911
Type:
Small organic molecule
Emp. Form.:
C15H14O5
Mol. Mass.:
274.2687
SMILES:
CCOc1c2ccoc2c(OCC)c2oc(=O)ccc12
Structure:
Search PDB for entries with ligand similarity: