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Target
Capsid protein
Ligand
BDBM50513198
Substrate
n/a
Meas. Tech.
ChEMBL_1852275 (CHEMBL4352899)
IC50
4070±n/a nM
Citation
 Qiu, J; Chen, W; Zhang, Y; Zhou, Q; Chen, J; Yang, L; Gao, J; Gu, X; Tang, D Assessment of quinazolinone derivatives as novel non-nucleoside hepatitis B virus inhibitors. Eur J Med Chem 176:41-49 (2019) [PubMed]  Article 
Target
Name:
Capsid protein
Synonyms:
Core antigen
Type:
PROTEIN
Mol. Mass.:
26278.39
Organism:
Hepatitis B virus
Description:
ChEMBL_450484
Residue:
230
Sequence:
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM50513198
Synonyms:
CHEMBL4536243
Type:
Small organic molecule
Emp. Form.:
C23H20N2O3S2
Mol. Mass.:
436.547
SMILES:
COc1ccc(cc1CSc1nc2ccccc2c(=O)n1Cc1cccs1)C(C)=O
Structure:
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