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Target
Capsid protein
Ligand
BDBM50513199
Substrate
n/a
Meas. Tech.
ChEMBL_1852275 (CHEMBL4352899)
IC50
1930±n/a nM
Citation
 Qiu, J; Chen, W; Zhang, Y; Zhou, Q; Chen, J; Yang, L; Gao, J; Gu, X; Tang, D Assessment of quinazolinone derivatives as novel non-nucleoside hepatitis B virus inhibitors. Eur J Med Chem 176:41-49 (2019) [PubMed]  Article 
Target
Name:
Capsid protein
Synonyms:
Core antigen
Type:
PROTEIN
Mol. Mass.:
26278.39
Organism:
Hepatitis B virus
Description:
ChEMBL_450484
Residue:
230
Sequence:
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM50513199
Synonyms:
CHEMBL4525697
Type:
Small organic molecule
Emp. Form.:
C27H31N3O3S2
Mol. Mass.:
509.683
SMILES:
CCN(CC)CCOc1ccc2nc(SCc3ccccc3OC)n(Cc3cccs3)c(=O)c2c1
Structure:
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