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Target
Kynureninase
Ligand
BDBM50069731
Substrate
n/a
Meas. Tech.
ChEMBL_91725 (CHEMBL702023)
IC50
20000±n/a nM
Citation
 Drysdale, MJ; Reinhard, JF S-aryl cysteine S,S-dioxides as inhibitors of mammalian kynureninase. Bioorg Med Chem Lett 8:133-8 (1999) [PubMed]  Article 
Target
Name:
Kynureninase
Synonyms:
KYNU_RAT | Kynu
Type:
PROTEIN
Mol. Mass.:
52470.50
Organism:
Rattus norvegicus
Description:
ChEMBL_91725
Residue:
464
Sequence:
MEPSPLELPVDAVRRIATELNCDPTDERVALRLDEEDKLKRFKDCFYIPKMRDLPSIDLSLVNEDDNAIYFLGNSLGLQPKMVKTYLEEELDKWAKIGAYGHEVGKRPWIIGDESIVSLMKDIVGAHEKEIALMNALTVNLHLLLLSFFKPTPKRHKILLEAKAFPSDHYAIESQIQLHGLDVEKSMRMIKPREGEETLRMEDILEVIEKEGDSIAVVLFSGLHFYTGQLFNIPAITQAGHAKGCFVGFDLAHAVGNVELHLHDWDVDFACWCSYKYLNSGAGGLAGAFIHEKHAHTIKPALVGWFGHELSTRFNMDNKLQLIPGVNGFRISNPPILLVCSLHASLEIFQQATMTALRRKSILLTGYLEYLLKHYHGGNDTENKRPVVNIITPSRAEERGCQLTLTFSISKKGVFKELEKRGVVCDKREPEGIRVAPVPLYNSFHDVYKFIRLLTAILDSTERN
  
Inhibitor
Name:
BDBM50069731
Synonyms:
2-Amino-3-(2-amino-3-fluoro-benzenesulfonyl)-propionic acid | CHEMBL29137
Type:
Small organic molecule
Emp. Form.:
C9H11FN2O4S
Mol. Mass.:
262.258
SMILES:
NC(CS(=O)(=O)c1cccc(F)c1N)C(O)=O
Structure:
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