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Target
Testis-specific chromodomain protein Y 1
Ligand
BDBM50515901
Substrate
n/a
Meas. Tech.
ChEMBL_1862779 (CHEMBL4363635)
Kd
1000±n/a nM
Citation
 Yang, L; Liu, Y; Fan, M; Zhu, G; Jin, H; Liang, J; Liu, Z; Huang, Z; Zhang, L Identification and characterization of benzo[d]oxazol-2(3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL. Eur J Med Chem 182:0 (2019) [PubMed]  Article 
Target
Name:
Testis-specific chromodomain protein Y 1
Synonyms:
CDY1 | CDY1A | CDY1B | CDY1_HUMAN | Testis-specific chromodomain protein Y 1
Type:
PROTEIN
Mol. Mass.:
60492.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116989
Residue:
540
Sequence:
MASQEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNRKLFAASKNVRRKAASILSDTKNMEIINSTIETLAPDSPFDHKTVSGFQKLEKLDPIAADQQDTVVFKVTEGKLLRDPLSRPGAEQTGIQNKTQIHPLMSQMSGSVTASMATGSATRKGIVVLIDPLAANGTTDMHTSVPRVKGGQRNITDDSRDQPFIKKMHFTIRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSKLVLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTFTQEVMIQIKELASYNPIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENKIDEF
  
Inhibitor
Name:
BDBM50515901
Synonyms:
CHEMBL1524534
Type:
Small organic molecule
Emp. Form.:
C16H14N2O4
Mol. Mass.:
298.2934
SMILES:
COc1cccc(NC(=O)Cn2c3ccccc3oc2=O)c1
Structure:
Search PDB for entries with ligand similarity: