Reaction Details Report a problem with these data
Target
Chromobox protein homolog 7
Ligand
BDBM50515894
Substrate
n/a
Meas. Tech.
ChEMBL_1862780 (CHEMBL4363636)
Kd
6100±n/a nM
Citation
 Yang, L; Liu, Y; Fan, M; Zhu, G; Jin, H; Liang, J; Liu, Z; Huang, Z; Zhang, L Identification and characterization of benzo[d]oxazol-2(3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL. Eur J Med Chem 182:0 (2019) [PubMed]  Article 
Target
Name:
Chromobox protein homolog 7
Synonyms:
CBX7 | CBX7_HUMAN | Chromobox protein homolog 7 | Chromobox protein homolog 7 (CBX7)
Type:
Protein
Mol. Mass.:
28351.76
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
251
Sequence:
MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKAGAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAPDVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF
  
Inhibitor
Name:
BDBM50515894
Synonyms:
CHEMBL4569763
Type:
Small organic molecule
Emp. Form.:
C18H18N2O4
Mol. Mass.:
326.3465
SMILES:
COc1ccc2oc(=O)n(CC(=O)c3ccc(cc3)N(C)C)c2c1
Structure:
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