Reaction Details Report a problem with these data
Target
Chromodomain Y-like protein
Ligand
BDBM50515927
Substrate
n/a
Meas. Tech.
ChEMBL_1862774 (CHEMBL4363630)
Kd
5800±n/a nM
Citation
 Yang, L; Liu, Y; Fan, M; Zhu, G; Jin, H; Liang, J; Liu, Z; Huang, Z; Zhang, L Identification and characterization of benzo[d]oxazol-2(3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL. Eur J Med Chem 182:0 (2019) [PubMed]  Article 
Target
Name:
Chromodomain Y-like protein
Synonyms:
4.2.1.- | CDY-like | CDYL | CDYL1 | CDYL_HUMAN | Chromodomain Y-like protein | Crotonyl-CoA hydratase | Synonyms=CDYL1
Type:
PROTEIN
Mol. Mass.:
66506.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116952
Residue:
598
Sequence:
MTFQASHRSAWGKSRKKNWQYEGPTQKLFLKRNNVSAPDGPSDPSISVSSEQSGAQQPPALQVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQVPGPVTAAMATGLAVNGKGTSPFMDALTANGTTNIQTSVTGVTASKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF
  
Inhibitor
Name:
BDBM50515927
Synonyms:
CHEMBL4531061
Type:
Small organic molecule
Emp. Form.:
C18H25N3O3
Mol. Mass.:
331.4094
SMILES:
CCN(CC)C1CCN(CC1)C(=O)Cn1c2ccccc2oc1=O
Structure:
Search PDB for entries with ligand similarity: