Reaction Details Report a problem with these data
Target
Cereblon isoform 4
Ligand
BDBM50516587
Substrate
n/a
Meas. Tech.
ChEMBL_1866003 (CHEMBL4366978)
Ki
11000±n/a nM
Citation
 Heim, C; Pliatsika, D; Mousavizadeh, F; Bär, K; Hernandez Alvarez, B; Giannis, A; Hartmann, MD De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives. J Med Chem 62:6615-6629 (2019) [PubMed]  Article 
Target
Name:
Cereblon isoform 4
Synonyms:
Cereblon isoform 4
Type:
PROTEIN
Mol. Mass.:
13620.40
Organism:
Magnetospirillum gryphiswaldense
Description:
ChEMBL_116733
Residue:
124
Sequence:
MPLDAGGQNSTQMVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPAD
  
Inhibitor
Name:
BDBM50516587
Synonyms:
CHEMBL4589159
Type:
Small organic molecule
Emp. Form.:
C12H7N3O6
Mol. Mass.:
289.2005
SMILES:
[O-][N+](=O)c1ccc2C(=O)N(C3CC(=O)NC3=O)C(=O)c2c1
Structure:
Search PDB for entries with ligand similarity: