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Target
CD209 antigen
Ligand
BDBM108233
Substrate
n/a
Meas. Tech.
ChEMBL_1868727 (CHEMBL4369793)
Kd
2600000±n/a nM
Citation
 Dalvit, C; Vulpetti, A Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects. J Med Chem 62:2218-2244 (2019) [PubMed]  Article 
Target
Name:
CD209 antigen
Synonyms:
C-type lectin domain family 4 member L | CD209 | CD209_HUMAN | CD_antigen=CD209 | CLEC4L | DC-SIGN | DC-SIGN1 | Dendritic cell-specific ICAM-3-grabbing non-integrin 1
Type:
PROTEIN
Mol. Mass.:
45768.84
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104194
Residue:
404
Sequence:
MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA
  
Inhibitor
Name:
BDBM108233
Synonyms:
1‐[2‐(trifluoromethyl)phenyl]piperazine hydrochloride (Hit 1)
Type:
Small organic molecule
Emp. Form.:
C11H13F3N2
Mol. Mass.:
230.2295
SMILES:
FC(F)(F)c1ccccc1N1CCNCC1
Structure:
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