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Target
CDGSH iron-sulfur domain-containing protein 2
Ligand
BDBM50030474
Substrate
n/a
Meas. Tech.
ChEMBL_1869768 (CHEMBL4370834)
IC50
2290±n/a nM
Citation
 Geldenhuys, WJ; Skolik, R; Konkle, ME; Menze, MA; Long, TE; Robart, AR Binding of thiazolidinediones to the endoplasmic reticulum protein nutrient-deprivation autophagy factor-1. Bioorg Med Chem Lett 29:901-904 (2019) [PubMed]  Article 
Target
Name:
CDGSH iron-sulfur domain-containing protein 2
Synonyms:
CDGSH iron-sulfur domain-containing protein 2 | CDGSH2 | CISD2 | CISD2_HUMAN | ERIS | Endoplasmic reticulum intermembrane small protein | Miner1 | MitoNEET-related 1 protein | NAF-1 | Nutrient-deprivation autophagy factor-1 | ZCD2
Type:
PROTEIN
Mol. Mass.:
15289.10
Organism:
Homo sapiens
Description:
ChEMBL_119149
Residue:
135
Sequence:
MVLESVARIVKVQLPAYLKRLPVPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV
  
Inhibitor
Name:
BDBM50030474
Synonyms:
Avandamet | Avandaryl | Avandia | BRL-49653 | CHEBI:50122 | Rosiglitazone | US10744117, Compound Rosiglitazone | US9562012, rosiglitazone
Type:
Small organic molecule
Emp. Form.:
C18H19N3O3S
Mol. Mass.:
357.427
SMILES:
CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1
Structure:
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