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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50073342
Substrate
n/a
Meas. Tech.
ChEMBL_157537 (CHEMBL764922)
Ki
3400±n/a nM
Citation
 Baker, CT; Salituro, FG; Court, JJ; Deininger, DD; Kim, EE; Li, B; Novak, PM; Rao, BG; Pazhanisamy, S; Schairer, WC; Tung, RD Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors. Bioorg Med Chem Lett 8:3631-6 (1999) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50073342
Synonyms:
CHEMBL121375 | N-Cyclopentylmethyl-N-[(S)-2-hydroxy-3-(3-methyl-1-phenethyl-ureido)-propyl]-4-methoxy-benzenesulfonamide
Type:
Small organic molecule
Emp. Form.:
C26H37N3O5S
Mol. Mass.:
503.654
SMILES:
CNC(=O)N(CCc1ccccc1)C[C@H](O)CN(CC1CCCC1)S(=O)(=O)c1ccc(OC)cc1
Structure:
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