Reaction Details Report a problem with these data
Target
Adenosine deaminase
Ligand
BDBM50519495
Substrate
n/a
Meas. Tech.
ChEMBL_1875742 (CHEMBL4377136)
Ki
0.007±n/a nM
Citation
 Cheviet, T; Lefebvre-Tournier, I; Wein, S; Peyrottes, S Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues. J Med Chem 62:8365-8391 (2019) [PubMed]  Article 
Target
Name:
Adenosine deaminase
Synonyms:
3.5.4.4 | Adenosine deaminase
Type:
PROTEIN
Mol. Mass.:
42457.37
Organism:
Plasmodium falciparum
Description:
ChEMBL_119120
Residue:
367
Sequence:
MNCKNMDTSYEIINYLTKDELDIDLSCMDKKERYKIWKRLPKCELHCHLDVCFSVDFFLNVIRKYNIQPNMSDEEIIDYYLFSKPGKSLDEFVEKALRLTDIYIDYTVVEDLAKHAVFNKYKEGVVLMEFRYSPSFMSFKHNLDKDLIHEAIVKGLNEAVALLEYKIQVGLLCTGDGGLSHERMKEAAEFCIKHKKDFVGYDHAGHEVDLKPFKDIFDNIREEGISLSVHAGEDVSIPNLNSLYTAINLLHVKRIGHGIRVSESQELIDLVKEKDILLEVCPISNVLLNNVKSMDTHPIRMLYDAGVKVSVNSDDPGMFLTNITDNYEELYTHLNFTLADFMKMNLWAVQKSFVDPDIKNKIISKYF
  
Inhibitor
Name:
BDBM50519495
Synonyms:
CHEMBL34023
Type:
Small organic molecule
Emp. Form.:
C11H16N4O5
Mol. Mass.:
284.2685
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2[C@@H](O)CN=CNc12 |c:17|
Structure:
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