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Target
Delta-type opioid receptor
Ligand
BDBM50073515
Substrate
n/a
Meas. Tech.
ChEMBL_146338 (CHEMBL753787)
Ki
23±n/a nM
Citation
 Negri, L; Lattanzi, R; Tabacco, F; Orrù, L; Severini, C; Scolaro, B; Rocchi, R Dermorphin and deltorphin glycosylated analogues: synthesis and antinociceptive activity after systemic administration. J Med Chem 42:400-4 (1999) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50073515
Synonyms:
CHEMBL405663 | N-(1-{1-[1-(3-Acetoxy-4,5,6-trihydroxy-tetrahydro-pyran-2-ylmethoxycarbonyl)-2-hydroxy-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-2-methyl-propyl)-3-{2-[2-(2-amino-2-[4-hydroxy-phenyl]-acetylamino)-propionylamino]-3-phenyl-propionylamino}-succinamic acid
Type:
Small organic molecule
Emp. Form.:
C44H63N7O17
Mol. Mass.:
962.0077
SMILES:
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)N[C@H](CO)C(=O)OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
Structure:
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