Reaction Details Report a problem with these data
Target
Scytalone dehydratase
Ligand
BDBM50078269
Substrate
n/a
Meas. Tech.
ChEBML_199522
Ki
0.240000±n/a nM
Citation
 Jordan, DB; Lessen, TA; Wawrzak, Z; Bisaha, JJ; Gehret, TC; Hansen, SL; Schwartz, RS; Basarab, GS Design of scytalone dehydratase inhibitors as rice blast fungicides: (N-phenoxypropyl)-carboxamides. Bioorg Med Chem Lett 9:1607-12 (1999) [PubMed]  Article 
Target
Name:
Scytalone dehydratase
Synonyms:
SCYD_MAGO7 | SDH1 | Scytalone dehydratase
Type:
PROTEIN
Mol. Mass.:
20248.63
Organism:
Magnaporthe grisea
Description:
ChEMBL_199536
Residue:
172
Sequence:
MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK
  
Inhibitor
Name:
BDBM50078269
Synonyms:
(R)-2-Cyano-N-[(R)-2-(3-fluoro-phenoxy)-1-methyl-ethyl]-3,3-dimethyl-butyramide | CHEMBL43852
Type:
Small organic molecule
Emp. Form.:
C16H21FN2O2
Mol. Mass.:
292.3485
SMILES:
C[C@H](COc1cccc(F)c1)NC(=O)[C@@H](C#N)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: