Reaction Details Report a problem with these data
Target
Scytalone dehydratase
Ligand
BDBM50078275
Substrate
n/a
Meas. Tech.
ChEBML_199522
Ki
0.370000±n/a nM
Citation
 Jordan, DB; Lessen, TA; Wawrzak, Z; Bisaha, JJ; Gehret, TC; Hansen, SL; Schwartz, RS; Basarab, GS Design of scytalone dehydratase inhibitors as rice blast fungicides: (N-phenoxypropyl)-carboxamides. Bioorg Med Chem Lett 9:1607-12 (1999) [PubMed]  Article 
Target
Name:
Scytalone dehydratase
Synonyms:
SCYD_MAGO7 | SDH1 | Scytalone dehydratase
Type:
PROTEIN
Mol. Mass.:
20248.63
Organism:
Magnaporthe grisea
Description:
ChEMBL_199536
Residue:
172
Sequence:
MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK
  
Inhibitor
Name:
BDBM50078275
Synonyms:
(R)-2,2-Dichloro-1-ethyl-3-methyl-cyclopropanecarboxylic acid [(R)-2-(2-fluoro-phenoxy)-1-methyl-ethyl]-amide | CHEMBL288484
Type:
Small organic molecule
Emp. Form.:
C16H20Cl2FNO2
Mol. Mass.:
348.24
SMILES:
CC[C@@]1(C(C)C1(Cl)Cl)C(=O)N[C@H](C)COc1ccccc1F
Structure:
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