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Target
Thiosulfate sulfurtransferase
Ligand
BDBM50247883
Substrate
n/a
Meas. Tech.
ChEMBL_1891102 (CHEMBL4392929)
IC50
94000±n/a nM
Citation
 Stevens, M; Abdeen, S; Salim, N; Ray, AM; Washburn, A; Chitre, S; Sivinski, J; Park, Y; Hoang, QQ; Chapman, E; Johnson, SM HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules. Bioorg Med Chem Lett 29:1106-1112 (2019) [PubMed]  Article 
Target
Name:
Thiosulfate sulfurtransferase
Synonyms:
2.8.1.1 | Rhodanese | THTR_HUMAN | TST | Thiosulfate sulfurtransferase
Type:
PROTEIN
Mol. Mass.:
33432.06
Organism:
Homo sapiens
Description:
ChEMBL_118080
Residue:
297
Sequence:
MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
  
Inhibitor
Name:
BDBM50247883
Synonyms:
CHEBI:28934 | Calciferol | Calciferol In Arach Oil | Caltrate | D-Forte | Deltalin | Drisdol | Eciferol D2 | Ergo-D2 | Ergocalciferol | Ergoral D2 | Lanes | Oleovitamin D | Oleovitamin D, Synthetic | Osto-D2 | Sterogyl | Sterogyl 15H | Sterogyl-15 | Uvesterol D | Viosterol in Oil | Vitamin D | Vitamin D 2 | Vitamin D2
Type:
Small organic molecule
Emp. Form.:
C28H44O
Mol. Mass.:
396.6484
SMILES:
[H][C@@]1(CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)CCC1=C)[C@H](C)\C=C\[C@H](C)C(C)C |r|
Structure:
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