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Target
Protein Tat
Ligand
BDBM50524905
Substrate
n/a
Meas. Tech.
ChEMBL_1895051 (CHEMBL4397086)
EC50
8000±n/a nM
Citation
 Nguyen, W; Jacobson, J; Jarman, KE; Jousset Sabroux, H; Harty, L; McMahon, J; Lewin, SR; Purcell, DF; Sleebs, BE Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models. J Med Chem 62:5148-5175 (2019) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | TAT_HV1H2 | tat
Type:
PROTEIN
Mol. Mass.:
9851.32
Organism:
Human immunodeficiency virus type 1 (isolate HXB2 group M subtype B)(HIV-1)
Description:
ChEMBL_320712
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAHQNSQTHQASLSKQPTSQPRGDPTGPKE
  
Inhibitor
Name:
BDBM50524905
Synonyms:
CHEMBL4546726
Type:
Small organic molecule
Emp. Form.:
C15H15BrN2O2
Mol. Mass.:
335.196
SMILES:
Brc1ccc(NC(=O)CCCOc2ccccc2)nc1
Structure:
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