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Target
Cannabinoid receptor 1
Ligand
BDBM50080032
Substrate
n/a
Meas. Tech.
ChEMBL_46804 (CHEMBL659691)
Ki
22.3±n/a nM
Citation
 Khanolkar, AD; Lu, D; Fan, P; Tian, X; Makriyannis, A Novel conformationally restricted tetracyclic analogs of delta8-tetrahydrocannabinol. Bioorg Med Chem Lett 9:2119-24 (1999) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50080032
Synonyms:
(4aR,12bR)-8-Hexyl-2,5,5-trimethyl-1,4a,5,8,9,10,11,12b-octahydro-4H-6-oxa-benzo[a]anthracen-12-ol | CHEMBL303479
Type:
Small organic molecule
Emp. Form.:
C26H38O2
Mol. Mass.:
382.5787
SMILES:
CCCCCCC1CCCc2c(O)c3[C@@H]4CC(C)=CC[C@H]4C(C)(C)Oc3cc12 |c:17|
Structure:
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