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Target
Histamine H3 receptor
Ligand
BDBM50408755
Substrate
n/a
Meas. Tech.
ChEMBL_86737 (CHEMBL693462)
EC50
0.25±n/a nM
Citation
 Sasse, A; Stark, H; Reidemeister, S; Hüls, A; Elz, S; Ligneau, X; Ganellin, CR; Schwartz, JC; Schunack, W Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity. J Med Chem 42:4269-74 (1999) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM50408755
Synonyms:
CHEMBL2145442
Type:
Small organic molecule
Emp. Form.:
C12H22N2O
Mol. Mass.:
210.3159
SMILES:
CC(C)CCCOCCCc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: