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Target
Free fatty acid receptor 3
Ligand
BDBM50527468
Substrate
n/a
Meas. Tech.
ChEMBL_1902654 (CHEMBL4404876)
EC50
407±n/a nM
Citation
 Ulven, ER; Quon, T; Sergeev, E; Barki, N; Brvar, M; Hudson, BD; Dutta, P; Hansen, AH; Bielefeldt, LŲ; Tobin, AB; McKenzie, CJ; Milligan, G; Ulven, T Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators. J Med Chem 63:3577-3595 (2020) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 3
Synonyms:
FFAR3_RAT | Ffar3 | Free fatty acid receptor 3 | G-protein coupled receptor 41 | Gpr41
Type:
PROTEIN
Mol. Mass.:
36493.02
Organism:
Rattus norvegicus
Description:
ChEMBL_117217
Residue:
319
Sequence:
MDTSFFPGNHWLFFSVDLLVFLVGLPLNVMALVVFVNKLRRRPVAVDLLLLNLTISDLLLLLFLPFRIVEAACGMKWILPFIFCPLSGFLFFTTIYLTSLFLMTVSIERFLSVAYPLWYKTRPRLAQAGLVSGICWFLASAHCSVIYVTEYWGNATYSQGTNGTCYLEFREDQLAILLPVRLEMAVVLFMVPLCITSYCYSRLVWILSQGASRRRRKRVMGLLVATLLIFFVCFGPYNMSHVVGYVRGESPTWRSYVLLLSTLNSCIDPLVFYFSSSKFQADFHQLLSRLIRACVPWTQEVSLELKVKNGEEPSKECPS
  
Inhibitor
Name:
BDBM50527468
Synonyms:
CHEMBL4530642
Type:
Small organic molecule
Emp. Form.:
C22H24Cl2N2O2
Mol. Mass.:
419.344
SMILES:
CC1=C(C(C2CCCC2)C2=C(CCCC2=O)N1)C(=O)Nc1cc(Cl)ccc1Cl |t:1,10|
Structure:
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