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Target
Carboxypeptidase A4
Ligand
BDBM50530231
Substrate
n/a
Meas. Tech.
ChEMBL_1911514 (CHEMBL4413960)
Ki
3.3±n/a nM
Citation
 Covaleda, G; Gallego, P; Vendrell, J; Georgiadis, D; Lorenzo, J; Dive, V; Aviles, FX; Reverter, D; Devel, L Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. J Med Chem 62:1917-1931 (2019) [PubMed]  Article 
Target
Name:
Carboxypeptidase A4
Synonyms:
3.4.17.- | CBPA4_HUMAN | CPA3 | CPA3 | CPA4 | Carboxypeptidase A3 | Carboxypeptidase A4
Type:
PROTEIN
Mol. Mass.:
47351.74
Organism:
Homo sapiens
Description:
ChEMBL_12937
Residue:
421
Sequence:
MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY
  
Inhibitor
Name:
BDBM50530231
Synonyms:
CHEMBL4528407
Type:
Small organic molecule
Emp. Form.:
C21H33N2O6P
Mol. Mass.:
440.4703
SMILES:
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](C)P(O)(=O)C[C@@H](CCc1ccccc1)C(O)=O |r|
Structure:
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