Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 5A
Ligand
BDBM34142
Substrate
n/a
Meas. Tech.
ChEMBL_3585 (CHEMBL618072)
Ki
4620.0±n/a nM
Citation
 Glennon, RA; Lee, M; Rangisetty, JB; Dukat, M; Roth, BL; Savage, JE; McBride, A; Rauser, L; Hufeisen, S; Lee, DK 2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors. J Med Chem 43:1011-8 (2000) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 5A
Synonyms:
5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:
Enzyme
Mol. Mass.:
40266.25
Organism:
Homo sapiens (Human)
Description:
P47898
Residue:
357
Sequence:
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
  
Inhibitor
Name:
BDBM34142
Synonyms:
2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL267615 | EDMT | EMDT | [2-(2-ethyl-5-methoxy-1H-indol-3-yl)ethyl]dimethylamine, 6
Type:
Small organic molecule
Emp. Form.:
C15H22N2O
Mol. Mass.:
246.348
SMILES:
CCc1[nH]c2ccc(OC)cc2c1CCN(C)C
Structure:
Search PDB for entries with ligand similarity: