Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50530597
Substrate
n/a
Meas. Tech.
ChEMBL_1913506 (CHEMBL4416089)
Ki
17±n/a nM
Citation
 Mallo-Abreu, A; Majellaro, M; Jespers, W; Azuaje, J; Caamaño, O; García-Mera, X; Brea, JM; Loza, MI; Gutiérrez-de-Terán, H; Sotelo, E Trifluorinated Pyrimidine-Based A J Med Chem 62:9315-9330 (2019) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50530597
Synonyms:
CHEMBL4469484
Type:
Small organic molecule
Emp. Form.:
C19H16F3N3O3
Mol. Mass.:
391.3438
SMILES:
C[C@@H](OC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1ccco1)C(F)(F)F |r,c:5|
Structure:
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