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Target
Cytochrome P450 2B6
Ligand
BDBM50531004
Substrate
n/a
Meas. Tech.
ChEMBL_1914332 (CHEMBL4416915)
IC50
>50000±n/a nM
Citation
 Adebesin, AM; Wesser, T; Vijaykumar, J; Konkel, A; Paudyal, MP; Lossie, J; Zhu, C; Westphal, C; Puli, N; Fischer, R; Schunck, WH; Falck, JR Development of Robust 17( J Med Chem 62:10124-10143 (2019) [PubMed]  Article 
Target
Name:
Cytochrome P450 2B6
Synonyms:
CP2B6_HUMAN | CYP2B6 | Cytochrome P450 2B6 (CYP2B6)
Type:
Protein
Mol. Mass.:
56289.75
Organism:
Homo sapiens (Human)
Description:
P20813
Residue:
491
Sequence:
MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR
  
Inhibitor
Name:
BDBM50531004
Synonyms:
CHEMBL1802692
Type:
Small organic molecule
Emp. Form.:
C19H34N2O4
Mol. Mass.:
354.4843
SMILES:
CNC(=O)C(=O)NCCCC\C=C/CCCCCCCCCC(O)=O
Structure:
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