Reaction Details Report a problem with these data
Target
Short transient receptor potential channel 5
Ligand
BDBM50532608
Substrate
n/a
Meas. Tech.
ChEMBL_1923378 (CHEMBL4426334)
IC50
<1.000000±n/a nM
Citation
 Abdel-Magid, AF Potential Treatment for Neuropsychiatry Disorders with TRPC5 Modulators. ACS Med Chem Lett 7:547-8 (2016) [PubMed]  Article 
Target
Name:
Short transient receptor potential channel 5
Synonyms:
TRP5 | TRPC5 | TRPC5_HUMAN | Transient receptor protein 5 (TRPC5)
Type:
Enzyme
Mol. Mass.:
111421.47
Organism:
Homo sapiens (Human)
Description:
Q9UL62
Residue:
973
Sequence:
MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRSFSTSSTELSQRDDNNDGSGGARAKSKSVSFNLGCKKKTCHGPPLIRTMPRSSGAQGKSKAESSSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQMEKGKAEACSQSEINLSEVELGEVQGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHKWGDGQEEQVTTRL
  
Inhibitor
Name:
BDBM50532608
Synonyms:
CHEMBL4525688
Type:
Small organic molecule
Emp. Form.:
C26H23F3N2O5
Mol. Mass.:
500.4664
SMILES:
Cn1c2ccc(Oc3cccc(OC(F)(F)F)c3)c(Cc3ccccc3)c2c(=O)n(CCCO)c1=O
Structure:
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