Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50533828
Substrate
n/a
Meas. Tech.
ChEMBL_1927387 (CHEMBL4430459)
Ki
>10000±n/a nM
Citation
 Köse, M; Schiedel, AC; Bauer, AA; Poschenrieder, H; Burbiel, JC; Akkinepally, RR; Stachel, HD; Müller, CE Focused screening to identify new adenosine kinase inhibitors. Bioorg Med Chem 24:5127-5133 (2016) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50533828
Synonyms:
CHEMBL4570031
Type:
Small organic molecule
Emp. Form.:
C12H10N6S3
Mol. Mass.:
334.443
SMILES:
Sc1nnc2c3c4CCCCc4sc3n3c(S)nnc3n12
Structure:
Search PDB for entries with ligand similarity: