Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50534494
Substrate
n/a
Meas. Tech.
ChEMBL_1929056 (CHEMBL4432232)
Ki
83±n/a nM
Citation
 Seltzman, HH; Shiner, C; Hirt, EE; Gilliam, AF; Thomas, BF; Maitra, R; Snyder, R; Black, SL; Patel, PR; Mulpuri, Y; Spigelman, I Peripherally Selective Cannabinoid 1 Receptor (CB1R) Agonists for the Treatment of Neuropathic Pain. J Med Chem 59:7525-43 (2016) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50534494
Synonyms:
CHEMBL4574099
Type:
Small organic molecule
Emp. Form.:
C28H27NO
Mol. Mass.:
393.5201
SMILES:
C(CC1=C\C(=C/c2ccccc2-c2ccccc2)c2ccccc12)N1CCOCC1 |t:2|
Structure:
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